Publications

Lab members are in orange, * = equal contribution, # = corresponding author

Original research papers

Zakarauskas-Seth B.I., Forcari G., Anandakumar H., Kotlar-Goldaper I., Barraud C., Jovanovic N., Brüning U., Kirwan J., Wilck N., Forslund S.K., Müller D.N., Filosa A., Sawamiphak S.
Dysbiosis drives cardiac diastolic remodeling in ion homeostatic dysregulation through impairment of indole-3 acetate-regulated hypocretin neuronal activity
Circulation Research, 2026, 138(6), e326990

Barraud C., Forcari G., Rauch A., Zakarauskas-Seth B.I., Batolomaeus H., Filosa A., Wilck N., Sawamiphak S.
Macrophage trafficking contributes to gut-brain crosstalk in hypertension
Circulation Research, 2025, 137(4), 572-575

Zaupa M., Nagaraj N., Sylenko A., Baier H., Sawamiphak S., Filosa A.^#
The Calmodulin-interacting peptide Pcp4a regulates feeding state-dependent behavioral choice in zebrafish
Neuron, 2024, 112(7), 1150-1164

Apaydin O., Altaikyzy A., Filosa A., Sawamiphak S.
Alpha-1 adrenergic signaling drives cardiac regeneration via extracellular matrix remodeling transcriptional program in zebrafish macrophages
Developmental Cell, 2023, 58(22), 2460-2476

Apaydin D.C., Zakarauskas-Seth B.I., Carnevale L., Apaydin O., Perrotta M., Carnevale R., Paraskevi Kotini M., Kotlar-Goldaper I., Belting H-G., Carnevale D.*, Filosa A.*, Sawamiphak S.
Interferon-gamma drives macrophage reprogramming, cerebrovascular remodeling, and cognitive dysfunction in a zebrafish and a mouse model of ion imbalance and pressure overload
Cardiovascular Research, 2023, 119 (5), 1234-1249

Corradi L., Zaupa M., Sawamiphak S., Filosa A.^#
Using pERK immunostaining to quantify neuronal activity induced by stress in zebrafish larvae
STAR Protocols, 2022, 3, 101731

Corradi L., Bruzzone M., Dal Maschio M., Sawamiphak S., Filosa A.^#
Hypothalamic Galanin-producing neurons regulate stress in zebrafish through a peptidergic, self-inhibitory loop
Current Biology, 2022, 32(7):1497-1510.e5

Apaydin D.C, Morocho Jaramillo P.A., Corradi L., Cosco F., Rathjen F.G., Kammertoens T., Filosa A.*, Sawamiphak S.*
Early-Life Stress Regulates Cardiac development through an Il-4-Glucocorticoid Signaling Balance
Cell Reports, 2020, 33: 108404

Bonnin E., Cabochette P., Filosa A., Juhlen R., Komatsuzaki S., Hezwani M., Dickmanns A., Martinelli V., Vermeersch M., Supply L., Martins N., Pirenne L., Ravenscroft G., Lombard M., Port S., Spillner C., Janssens S., Roets E., Van Dorpe J., Lammens M., Kehlenbach R.H., Ficner R., Laing N., Hoffmann K., Vanhollebeke B., Fahrenkrog B.
Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence
PLOS Genetics, 2018, doi.org/10.1371/journal.pgen.1007845

Sawamiphak S., Kontarakis Z., Filosa A., Reischauer S., Stainier D.Y.R.
Transient cardiomyocyte fusion regulates cardiac development in zebrafish
Nature Communications, 2017, doi: 10.1038/s41467-017-01555-8

Förster D., Arnold-Ammer I., Laurell E., Barker A., Fernandes A.M., Finger-Baier K., Filosa A., Helmbrecht T., Kölsch Y., Kühn E., Robles E., Slanchev K., Thiele T., Baier H., Kubo F.
Genetic targeting and anatomical registration of neuronal populations in the zebrafish brain with a new set of BAC transgenic tools
Scientific Reports, 2017, 12;7(1):5230. doi: 10.1038/s41598-017-04657-x

Filosa A., Barker A.J., Dal Maschio M., Baier H.
Feeding State Modulates Behavioral Choice and Processing of Prey Stimuli in the Zebrafish Tectum
Neuron, 2016, 90(3), 596-608

Robles E., Filosa A., Baier H.
Precise lamination of retinal axons generates multiple parallel input pathways in the tectum
Journal of Neuroscience, 2013, 33(11):5027–5039

Akerboom J., Chen T.W., Wardill T.J., Tian L., Marvin J.S., Mutlu S., Carreras Calderon N., Esposti F., Borghuis B.G., Sun X.R., Gordus A., Orger M.B., Portugues R., Engert F., Macklin J.J., Filosa A., Aggarwal A., Kerr R.A., Takagi R., Kracun S., Shigetomi E., Khakh B.S., Baier H., Lagnado L., Wang S.S-H., Bargmann C.I., Kimmel B.E., Jayaraman V., Svoboda K., Kim D.S., Schreiter E.R., Looger L.L.
Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging
Journal of Neuroscience, 2012, 32(40):13819-13840

Filosa A.*, Paixão S.*, Honsek S.D., Carmona M.A., Becker L., Feddersen B., Gaitanos L., Rudhard Y., Schoepfer R., Klopstock T., Kullander K., Rose C.R., Pasquale E.B., Klein R.
Neuron-glia communication via EphA4/ephrinA3 modulates LTP through glial glutamate transport
Nature Neuroscience, 2009, 12, 1285-1292

Wegmeyer H., Egea J., Rabe N., Gezelius H., Filosa A., Enjin A., Veroqueaux F., Deininger K., Schnuetgen F., Brose N., Klein R., Kullander K., Betz A.
EphA4-dependent axon guidance is mediated by the RacGAP a2-chimaerin
Neuron 55, 2007, 756-767

Armentano M., Filosa A., Andolfi G., Studer M.
COUP-TFI is required for the formation of commissural projections in the forebrain by regulating axonal growth
Development, 2006, 133, 4151-4162

Studer M., Filosa A., Rubenstein J.L.R.
The nuclear receptor COUP-TFI represses differentiation of Cajal-Retzius cells
Brain Research Bulletin, 2005, 66, 394-401

Tripodi M.*, Filosa A.*, Armentano M., Studer M.
The COUP-TF nuclear receptors regulate cell migration in the mammalian basal forebrain
Development, 2004, 131, 6119-6129

Reviews

Filosa A., Sawamiphak S.
Heart development and regeneration—a multi-organ effort
The FEBS Journal, 2023, doi: 10.1111/febs.16319

Corradi L., Filosa A.^#
Neuromodulation and behavioral flexibility in larval zebrafish: from neurotransmitters to circuits
Frontiers in Molecular Neuroscience, 2021, doi: 10.3389/fnmol.2021.718951

Book chapters

Filosa A. and Klein R.
Ephrins and Eph receptors – Synaptogenesis and Synaptic Function
In: Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections (Rakic P. and Rubenstein J.L.R., ed) Elsevier, 2013, 659-670